DLScat

Nano Particle Sizing

Precise. Flexible. Reliable.

The DLScat is an enhanced particle size measurement solution, which exploits multiangle dynamic light scattering combined with an intelligent intensity spike filtering algorithm. It determines particle size more accurately and reliably in a large variety of samples, especially those containing contaminants, agglomerates, or polydisperse particles.

Maximize Accuracy with Intelligent Intensity Spike Filtering
Contaminants and agglomerates are some of the most common problems in DLS measurements and can lead to significantly distorted measurements. In traditional DLS solutions, a single "spike" by such a contaminant or agglomerate is enough to result in erroneously large particle size measurements. The intelligent intensity spike filtering developed by Swabian Instruments for the DLScat effortlessly eliminates these spikes from the scattered light. This recovers the correlation function and ensures precise measurement without prior cumbersome sample filtering procedures, saving the researcher's valuable time.
Immediate Consistency Checks with up to 6 Scattering Angles
The most stringent method to confirm that a DLS particle size measurement was correct is to check the similarity of the measurements across multiple scattering angles. That is what makes multiangle dynamic light scattering so powerful. Existing DLS instruments allow to measure only one angle at a time. Therefore, a multi-angle measurement is tedious and time-consuming, preventing users from performing this valuable consistency check. Our DLScat measures at up to 6 angles in one shot, enabling effortless consistency checks promptly and routinely.

Dynamic Light Scattering (DLS) - Benefits and Challenges

Dynamic Light Scattering (DLS) is a fast, convenient, non-invasive optical method for assessing particle sizes in solution, widely used for sample quality validation. The main limitation of existing DLS systems is susceptibility to large particles such as dust or agglomerates, which bias the apparent particle size towards erroneous larger values. Our DLScat offers not only a solution for such contaminated samples but also gives unparalleled control over advanced analysis parameters, allowing you to access the latest capabilities of DLS.

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Specifications

Particle Size Specifications
Size Range0.3 nm – 10 µm hydrodynamic diameter *
Geometric Angles20° (forward scattering); 69°, 90°, 111° (side scattering); 157° (back scattering)
AnalysisCONTIN, Cumulant analysis, Intensity spike filtering, Kinetics
Temperature Range16 °C – 100 °C (+/- 0.1 °C) **
Sample Characteristics
Minimum Concentration0.1 mg/mL (lysozyme), 0.1 ppm (latex 100 nm diameter) *
Maximum Concentration40% w/v *
Minimum Volume12 µL (1-angle), 50 µL (3-angles), 100 µL (5-angles)
Optics - Laser
Laser Wavelength633 nm (561 nm and other wavelengths available upon request)
Laser Powertunable, 3 – 30 mW (wavelength-dependent)
Laser Safety ClassClass 1
Laser Warmup Time1 min
Optics - Detector
Detector TypeSingle-mode fiber coupled with high-performance SPAD
Number of Detectors1-angle, 3-angle, 5-angle configurations available
Attenuation Range1 – 1000
Number of Binsup to 500
System & Interface
DimensionsL: 485 mm, W: 330 mm, H: 230 mm, weight approx. 16 kg
CorrelatorTime Tagger, auto- or pseudo-cross-correlation
Digital CommunicationUSB 2.0 Type C connection
ComputerIncluded, Mini PC
SoftwareWindows 11, Graphical user interface
Particle Size Specifications
Size Range
0.3 nm – 10 µm hydrodynamic diameter *
Geometric Angles
20° (forward scattering); 69°, 90°, 111° (side scattering); 157° (back scattering)
Analysis
CONTIN, Cumulant analysis, Intensity spike filtering, Kinetics
Temperature Range
16 °C – 100 °C (+/- 0.1 °C) **
Sample Characteristics
Minimum Concentration
0.1 mg/mL (lysozyme), 0.1 ppm (latex 100 nm diameter) *
Maximum Concentration
40% w/v *
Minimum Volume
12 µL (1-angle), 50 µL (3-angles), 100 µL (5-angles)
Optics - Laser
Laser Wavelength
633 nm (561 nm and other wavelengths available upon request)
Laser Power
tunable, 3 – 30 mW (wavelength-dependent)
Laser Safety Class
Class 1
Laser Warmup Time
1 min
Optics - Detector
Detector Type
Single-mode fiber coupled with high-performance SPAD
Number of Detectors
1-angle, 3-angle, 5-angle configurations available
Attenuation Range
1 – 1000
Number of Bins
up to 500
System & Interface
Dimensions
L: 485 mm, W: 330 mm, H: 230 mm, weight approx. 16 kg
Correlator
Time Tagger, auto- or pseudo-cross-correlation
Digital Communication
USB 2.0 Type C connection
Computer
Included, Mini PC
Software
Windows 11, Graphical user interface

A controlled working environment is required to meet all the specifications mentioned.

* Sample performance metrics are sample-dependent.

** Temperatures down to 0 °C are achievable with external dry-air purging to prevent condensation.

DLScat Applications
Industries:
  • Life sciences
  • Food industry
  • Beauty industry
  • Pharma industry
  • Nanotechnology
Systems:
  • Nanoparticles
  • Micelles
  • Colloids
  • Vesicles
  • Proteins
Are you searching for a custom-built DLS device?

Do you need a certain wavelength, want to measure at a specific angle, or include a special analysis algorithm? Our modular DLS system enables us to accommodate your experimental demands. We'd love to learn about your wishes.

Contact our DLS team
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