DLScat

Nano Particle Sizing

Precise. Flexible. Reliable.

The DLScat is an enhanced particle size measurement solution, which exploits multiangle dynamic light scattering combined with an intelligent intensity spike filtering algorithm. It determines particle size more accurately and reliably in a large variety of samples, especially those containing conta minants, agglomerates, or polydisperse particles.

Maximize Accuracy with Intelligent Intensity Spike Filtering
Contaminants and agglomerates are some of the most common problems in DLS measurements and can lead to significantly distorted measurements. In traditional DLS solutions, a single "spike" by such a contaminant or agglomerate is enough to result in erroneously large particle size measurements. The intelligent intensity spike filtering developed by Swabian Instruments for the DLScat effortlessly eliminates these spikes from the scattered light. This recovers the correlation function and ensures precise measurement without prior cumbersome sample filtering procedures, saving the researcher's valuable time.
Immediate Consistency Checks with up to 6 Scattering Angles
The most stringent method to confirm that a DLS particle size measurement was correct is to check the similarity of the measurements across multiple scattering angles. That is what makes multiangle dynamic light scattering so powerful. Existing DLS instruments allow to measure only one angle at a time. Therefore, a multi-angle measurement is tedious and time-consuming, preventing users from performing this valuable consistency check. Our DLScat measures at up to 6 angles in one shot, enabling effortless consistency checks promptly and routinely.

Dynamic Light Scattering (DLS) - Benefits and Challenges

Dynamic Light Scattering (DLS) is a fast, convenient, non-invasive optical method for assessing particle sizes in solution, widely used for sample quality validation. The main limitation of existing DLS systems is susceptibility to large particles such as dust or agglomerates, which bias the apparent particle size towards erroneous larger values. Our DLScat offers not only a solution for such contaminated samples but also gives unparalleled control over advanced analysis parameters, allowing you to access the latest capabilities of DLS.

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Specifications

Dynamic Light Scattering
Size Range0.3 nm - 10 μm (diameter) *
Scattering Angle15°, 74°, 90°, 106°, 163°
AnalysisIntensity Spike Filtering, CONTIN, Cumulant analysis
Temperature Range0 °C - 100 °C (+/- 0.05 °C)
Sample Characteristics
Minimum Concentration0.1 mg/mL (lysozyme), 0.1 ppm (Latex 100 nm diameter)
Maximum Concentration40 % w/v (sample-dependent)
Minimum Sample Volume4 μL - 4mL
Optics
Laser Wavelength561 nm or 633 nm (other wavelength available upon request)
Laser Power3 - 30 mW **
Attenuation Range1 - 10000
DetectorSingle mode fiber coupled with high performance SPAD
Laser Safety ClassClass 1
Laser warmup timeImmediately ***
Number of binsup to 500
Other characteristics
DimensionsL: 485 mm, W: 330 mm, H: 230 mm, weight approx. 16 kg
Digital CommunicationUSB 2.0 Type C connection
CorrelatorTime Tagger, auto- and cross-correlation
ComputerWindows 10/11
SoftwareGraphical user interface and API available
Dynamic Light Scattering
Size Range
0.3 nm - 10 μm (diameter) *
Scattering Angle
15°, 74°, 90°, 106°, 163°
Analysis
Intensity Spike Filtering, CONTIN, Cumulant analysis
Temperature Range
0 °C - 100 °C (+/- 0.05 °C)
Sample Characteristics
Minimum Concentration
0.1 mg/mL (lysozyme), 0.1 ppm (Latex 100 nm diameter)
Maximum Concentration
40 % w/v (sample-dependent)
Minimum Sample Volume
4 μL - 4mL
Optics
Laser Wavelength
561 nm or 633 nm (other wavelength available upon request)
Laser Power
3 - 30 mW **
Attenuation Range
1 - 10000
Detector
Single mode fiber coupled with high performance SPAD
Laser Safety Class
Class 1
Laser warmup time
Immediately ***
Number of bins
up to 500
Other characteristics
Dimensions
L: 485 mm, W: 330 mm, H: 230 mm, weight approx. 16 kg
Digital Communication
USB 2.0 Type C connection
Correlator
Time Tagger, auto- and cross-correlation
Computer
Windows 10/11
Software
Graphical user interface and API available

The ideal working environment (room temperature ≤ 23 °C, relative humidity ≤ 70%) is required to meet all the specifications mentioned. Purging of a dry air source is required for temperatures below the dew point.

* The size is defined as Hydrodynamic diameter. As for all DLS instruments, the maximum range is sample-dependent.

** The laser power range is wavelength-dependent. For a 633 nm laser, the range is 3 - 30 mW and can be manually adjusted (30 mW is the maximum value).

*** The laser warmup time is laser-dependent and varies from less than 5 s to 1 min depending on the chosen laser.

DLScat Applications
Industries:
  • Life sciences
  • Food industry
  • Beauty industry
  • Pharma industry
  • Nanotechnology
Systems:
  • Nanoparticles
  • Micelles
  • Colloids
  • Vesicles
  • Proteins
Are you searching for a custom-built DLS device?

Do you need a certain wavelength, want to measure at a specific angle, or include a special analysis algorithm? Our modular DLS system enables us to accommodate your experimental demands. We'd love to learn about your wishes.

Contact our DLS team

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