Dynamic Light Scattering and Precise Timing at Photonic West 2026

作者 Maré Sutphen | 日期 19 February 2026

The Swabian Instruments team returned to San Francisco this January for the 2026 Photonics West conference. We had the pleasure of demonstrating our devices at the exhibition. connecting with experts in the materials science and photonics & optics fields, and met with users to discuss their experiences and feedback. Our team enjoyed the chance to talk with existing users about their experiences with our devices and collect feedback. We addressed our users’ questions and connected them with our support team for further assistance.

Swabian Instruments team members at one of the exhibition booths for BiOS, standing in front of the informational walls about TCSPC and Dynamic Light Scattering using the Time Tagger Series. From left to right: Michael Schlagmüller, Maré Sutphen, and Ginger Geng.
The Swabian Instruments team at the BiOS booth. From left to right: Michael Schlagmüller, Maré Sutphen, and Ginger Geng.
Swabian Instruments team members at one of the exhibition booths for BiOS, standing behind a monitor that displays a fluorescence lifetime measurement using a Time Tagger. The team is standing in front of the informational walls that explain the measurements possible with the Time Tagger Series. From left to right: Thomas Hayes, Mireia Perera Gonzalez, Yizhou Wang.
The Swabian Instruments team at the BiOS booth. From left to right: Thomas Hayes, Mireia Perera Gonzalez, Yizhou Wang.

Demonstrating our Dynamic Light Scattering System at the BiOS Exhibition

This year, we had two booth locations at the BiOS show, which takes place on the first 2 days of the conference. Our first booth showcased our turnkey Dynamic Light Scattering (DLS) solution, DLScat. Many conversations focused on the value of multi-angle DLS for kinetic experiments, particularly for tracking aggregation, binding, or structural evolution in real time. DLScat approaches particle size analysis differently by leveraging the capabilities of the Time Tagger 20 to enable simultaneous multi-angle DLS (MASDLS) with up to five angles and real-time analysis. This provides higher information density per measurement and allows users to access raw photon streams for post-processing, such as re-binning in time, re-computing correlations, or applying advanced filtering without re-acquiring data.

In some conversations, we also learned that there is an interest in DLS and fluorescence correlation spectroscopy (FCS) within a single measurement platform, reflecting growing interest in hybrid approaches for studying dynamics across different contrast mechanisms. These exchanges highlighted how DLScat is particularly well suited for kinetic studies of evolving systems, as well as polydisperse, temperature-dependent, or otherwise challenging samples.

Lifetime Measurements, Timing & Frequency Analysis, and the Beloved Button Presser Game at the Photonics West Exhibition

Once again, our Photonics West booth was a hub for live demonstrations of the Time Tagger and Pulse Streamer Series.

  • Frequency Stability Analysis & Phase Noise Analysis
    • We demonstrated phase noise and frequency stability analysis of three oscillators using the Time Tagger X. The platform supports interactive analysis via Time Tagger Lab and programmatic control through Python/MATLAB APIs for automated workflows. Phase noise quantifies the short-term timing jitter to reveal how an oscillator’s phase randomly fluctuates slow phase variations, and frequency stability measures long-term drift to evaluate how an oscillator maintains its frequency over time. Together, these parameters are critical in precise timing applications, when even the smallest deviations matter. Through characterizing multiple clocks, researchers can compare and better understand system performance. The Time Tagger X provides 1.5 ps timing jitter with multichannel simultaneous acquisition, enabling precise characterization of oscillator instabilities. This is critical for optical frequency combs, quantum communication synchronization, and precision spectroscopy applications.
  • Fluorescence Lifetime
    • We performed live fluorescence lifetime measurements using time-correlated single photon counting (TCSPC). The Pulse Streamer 8/2 generated excitation pulses to trigger the laser, while the Time Tagger 20 timestamped both excitations and detections and streamed data to the PC. Time Tagger Lab enabled real-time visualization of excited-state decay histograms, critical for materials science, fluorescence sensors, and cellular imaging applications.
  • Upcoming Signal Generation
    • Lastly, we showed a sneak peek of our upcoming Pulse Streamer X. Our newest addition to our pulse generation series is planned to feature:
      • Up to 32 digital outputs, <10 ps RMS timing jitter
      • Amplitude up to 3.0V in 50Ω (adjustable)
      • Gbit/s streaming, 1 ns minimum pulse width
      • 10Gbit/s Ethernet (SFP+) and USB 3.0
      • Flexible (4x) trigger inputs
      • User-friendly API

User Research Highlights: Single-Photon Detection and Biomedical Imaging

We had the opportunity to attend some of our users’ presentations about their research, such as:

  • Prof. Melissa Skala from Morgridge Institute for Research was featured as one of the BiOS Hot Topic speakers and presented her efforts on Advancing immunotherapy with single-cell autofluorescence lifetime technologies in this session, as well as a number of technical presentations. Her impactful work applies advanced optical imaging approaches to study immune responses and cellular metabolism, with applications ranging from cancer immunotherapy and cell therapy development to clinically driven challenges such as treatment personalization and therapy quality control.

  • Yifan Li, a student in Prof. Qiu’s group at Michigan State University, presented his work on fluorescence confocal microscopy and swept-source Raman spectroscopy enabled by SNSPDs. This project demonstrates how time-resolved single-photon detection supports deep-tissue NIR-II fluorescence imaging and femtomolar-level Raman sensitivity at low excitation powers.

Our customers are at the heart of what we do. Feedback drives our development, and we are always looking to improve and further understand how we can best support scientists using our systems (more in our recent blog post highlighting our ongoing commitment to providing high-quality, application-driven support). We held some deeply technical discussions surrounding very high-speed acquisitions, new measurement classes, integration with unique detection schemes, and advancements in Photon Number Resolution applications. To ensure we can support you as best as possible any time, our team has developed an in-depth FAQ.

If we did not get the chance to connect at the show, we would love to hear from you! You can find us at solutions@swabianinstruments.com. We’re looking forward to learning about your experience, research, and requirements to identify how we could best support you.

Thank you to the organizers at SPIE, our collaborators, and all those who stopped by our booths. We are grateful for the conversations we had at the conference and are already looking forward to next year!

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Swabian Instruments’ Commitment to Customer Success

Swabian Instruments delivers fast, expert-level support led by application scientists specializing in photonics, quantum optics, timing & frequency, life sciences, and software development. With an average first-response time of four hours, users receive reliable guidance, complemented by extensive documentation, Python examples, and a comprehensive FAQ, to troubleshoot and optimize experimental setups.

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